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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  6.00E+5nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed