Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
IC50: 20nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
IC50: 2.10E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
IC50: 4.00E+3nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
IC50: 4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
BDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)