Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Non-lysosomal glucosylceramidase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50335395
(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Ceramide glucosyltransferase
(Mus musculus)
TBA
Curated by
ChEMBL
Ligand
BDBM50335395
(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-galactosidase
(Mus musculus)
TBA
Curated by
ChEMBL
Ligand
BDBM50335395
(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.00E+5nM
Assay Description:
Inhibition of lactase in mouse intestinal input by glucose release assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysosomal acid glucosylceramidase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50335395
(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+5nM
Assay Description:
Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sucrase-isomaltase
(Mus musculus)
TBA
Curated by
ChEMBL
Ligand
BDBM50335395
(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of sucrase in mouse intestinal input by glucose release assay
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysosomal alpha-glucosidase
(Mus musculus (Mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50335395
(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of maltase in mouse intestinal input by glucose release assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI