Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 23 hits in this display
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
Ki: 1nMAssay Description:Inhibition of PGD2-induced CRTH2 receptor internalization of CD16 negative granulocytes in human whole blood by flow cytometryMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
Ki: 148nMAssay Description:Antagonist activity at DP receptor in human platelets assessed as inhibition of PGD2-induced cAMP production by competitive ELISAMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 3nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 receptor expressed in human HEK293 cells by scintillation counter in presence of 0.5% bovine serum albuminMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 3nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK293 cells in buffer solution with 0.5% bovine serum albumin by scintillation countingMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 3nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSAMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 12nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSAMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 12nMAssay Description:Displacement of [3H]-PGD2 from human DP receptor expressed in HEK 293 cells in presence of 0.5% BSA by scintillation countingMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 21nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasmaMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 21nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 receptor expressed in human HEK293 cells by scintillation counter in presence of 50% human plasmaMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 21nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells by scintillation counting in presence of 50% plasmaMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 280nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
IC50: 280nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasmaMore data for this Ligand-Target Pair
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)
BDBM50302828(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)