Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL

LigandBDBM50556431(CHEMBL4762900)Copy SMILESCopy InChI

Affinity DataKd:  3.82E+4nMAssay Description:Binding affinity to His-tagged human CFTR-F508del mutant by surface plasmon resonance assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL

LigandBDBM50556431(CHEMBL4762900)Copy SMILESCopy InChI

Affinity DataEC50:  17nMAssay Description:Correction activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells coexpressing HS-YFP preincubated for 24 hrs followed by forsk...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI