Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 20S immunoproteasome beta-1i subunit using (Ac-PAL)2R110 as substrate preincubated for 2 hrs followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50:  41nMAssay Description:Inhibition of human 20S proteasome beta5 subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta-2i subunit using Ac-RLR-AMC as substrate preincubated for 2 hrs followed by substrate addition and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProteasome subunit beta type-6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of human 20S immunoproteasome beta1 subunit using Ac-nLPnLD-AMC as substrate preincubated for 2 hrs followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetProteasome subunit beta type-7(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50601642(CHEMBL5188533)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human 20S proteasome beta2 subunit using Ac-RLR-AMC as substrate preincubated for 2 hrs followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed