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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Acetyl-coenzyme A synthetase, cytoplasmic
(Homo sapiens)
Smith, Gambrell & Russell
Curated by
ChEMBL
Ligand
BDBM50574374
(CHEMBL4850648 | US20230271956, Compound 87)
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Affinity Data
IC50: 0.0100nM
Assay Description:
Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assay
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Acetyl-coenzyme A synthetase, cytoplasmic
(Homo sapiens)
Smith, Gambrell & Russell
Curated by
ChEMBL
Ligand
BDBM50574374
(CHEMBL4850648 | US20230271956, Compound 87)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0100nM
Assay Description:
Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetyl-coenzyme A synthetase, cytoplasmic
(Homo sapiens)
Smith, Gambrell & Russell
Curated by
ChEMBL
Ligand
BDBM50574374
(CHEMBL4850648 | US20230271956, Compound 87)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetyl-coenzyme A synthetase, cytoplasmic
(Homo sapiens)
Smith, Gambrell & Russell
Curated by
ChEMBL
Ligand
BDBM50574374
(CHEMBL4850648 | US20230271956, Compound 87)
Copy SMILES
Copy InChI
Affinity Data
IC50: <1nM
Assay Description:
The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Acetyl-coenzyme A synthetase, cytoplasmic
(Homo sapiens)
Smith, Gambrell & Russell
Curated by
ChEMBL
Ligand
BDBM50574374
(CHEMBL4850648 | US20230271956, Compound 87)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.5nM
Assay Description:
The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI