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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50333869
((R)-2-(3-chloro-7-(4-fluoro-N-methylphenylsulfonam...)
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Affinity Data
Ki: 1.10nM
Assay Description:
Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50333869
((R)-2-(3-chloro-7-(4-fluoro-N-methylphenylsulfonam...)
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Copy InChI
Affinity Data
Ki: 104nM
Assay Description:
Binding affinity to prostanoid DP1 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50333869
((R)-2-(3-chloro-7-(4-fluoro-N-methylphenylsulfonam...)
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Affinity Data
Ki: 3.95E+3nM
Assay Description:
Binding affinity to thromboxane receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50333869
((R)-2-(3-chloro-7-(4-fluoro-N-methylphenylsulfonam...)
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Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50333869
((R)-2-(3-chloro-7-(4-fluoro-N-methylphenylsulfonam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape change
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI