Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCapsid protein(Hepatitis B virus)
Novira Therapeutics

Curated by ChEMBL

LigandBDBM324426(US10189835, Compound 912)Copy SMILESCopy InChI

Affinity DataEC50:  200nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/TrEMBL
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCapsid protein(Hepatitis B virus genotype C subtype ayr (isolate ...)
Novira Therapeutics

US Patent

LigandBDBM324426(US10189835, Compound 912)Copy SMILESCopy InChI

Affinity DataEC50: <500nMAssay Description:HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI