Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL

LigandBDBM50240208(CHEMBL4099012)Copy SMILESCopy InChI

Affinity DataIC50:  270nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL

LigandBDBM50240208(CHEMBL4099012)Copy SMILESCopy InChI

Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI