Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetCoagulation factor X(Oryctolagus cuniculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi:  17nMAssay Description:Binding affinity to rabbit factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi:  27nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi:  27nMAssay Description:Binding affinity to factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of factor 9aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of factor 11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of tissue factor/factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataKi: >3.30E+4nMAssay Description:Inhibition of activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50324745((3R,4R)-methyl 3-(5-chloropyridin-2-ylcarbamoyl)-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed