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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Protein Wnt-3a
(Homo sapiens (Human))
Novartis
US Patent
Ligand
BDBM374968
(US10251893, Cpd 166)
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Affinity Data
IC50: 0.100nM
Assay Description:
Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Protein-serine O-palmitoleoyltransferase porcupine
(Mus musculus)
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM374968
(US10251893, Cpd 166)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.100nM
Assay Description:
Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Protein-serine O-palmitoleoyltransferase porcupine
(Mus musculus)
Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM374968
(US10251893, Cpd 166)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.100nM
Assay Description:
Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI