Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetProgesterone receptor(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivationMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity against progesterone receptor in human T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at progesterone receptor by cellular reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  6.10nMAssay Description:Antagonist activity at human AR ligand binding domain expressed in african green monkey COS7 cells in presence of 5-alpha-dihydrotestosterone by Gal4...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at androgen receptor by cellular reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at human GR ligand binding domain expressed in african green monkey COS7 cells in presence of Dexamethasone by Gal4 hybrid assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at glucocorticoid receptor by cellular reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor by cellular reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at human MR ligand binding domain expressed in african green monkey COS7 cells in presence of aldosterone by Gal4 hybrid assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  1.90E+3nMAssay Description:Antagonist activity at human ER ligand binding domain expressed in african green monkey COS7 cells in presence of 17-beta-estradiol by Gal4 hybrid as...More data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at estrogen receptor by cellular reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50375423(ASOPRISNIL)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human PRB expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoMMDBPC cidPC sid
In DepthDetails ArticlePubMed