Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine

Curated by ChEMBL

LigandBDBM50542023(CHEMBL4649653)Copy SMILESCopy InChI

Affinity DataIC50:  66nMAssay Description:Allosteric inhibition of His-tagged CPS1 (unknown origin) expressed in baculovirus infected Sf21 insect cells assessed as reduction in ADP level prei...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbamoyl-phosphate synthase [ammonia], mitochondrial(Homo sapiens)
H3 Biomedicine

Curated by ChEMBL

LigandBDBM50542023(CHEMBL4649653)Copy SMILESCopy InChI

Affinity DataIC50:  240nMAssay Description:Inhibition of CPS1 in human pooled hepatocytes assessed as reduction in urea production measured after 16 hrs in presence of NH4Cl by tecan-plate rea...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI