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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Cathepsin D
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM50055910
(CHEMBL3321923 | US9884814, Compound 13)
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Affinity Data
IC50: 180nM
pH: 5.5 T: 2°C
Assay Description:
In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Cathepsin D
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM50055910
(CHEMBL3321923 | US9884814, Compound 13)
Copy SMILES
Copy InChI
Affinity Data
IC50: 320nM
Assay Description:
Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Renin
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50055910
(CHEMBL3321923 | US9884814, Compound 13)
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Affinity Data
IC50: 2.70E+4nM
Assay Description:
Inhibition of human recombinant renin using quenched Dabcyl-g-Abu-IHPFHLVIHT-Edans peptide substrate by fluorescence-based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI