Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL

LigandBDBM50428029(CHEMBL1257063)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:Inhibition of porcupine activity (unknown origin) expressed in human HT1080 cells assessed as suppression of Wnt3A-mediated super top flash activity ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
The University Of Texas Southwestern Medical Center

Curated by ChEMBL

LigandBDBM50428029(CHEMBL1257063)Copy SMILESCopy InChI

Affinity DataEC50:  60nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI