Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetSmoothened homolog(Mus musculus)
Soochow University

Curated by ChEMBL

LigandBDBM50428046(CHEMBL2324271)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
The University Of Texas Southwestern Medical Center

Curated by ChEMBL

LigandBDBM50428046(CHEMBL2324271)Copy SMILESCopy InChI

Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of porcupine-mediated Wnt signalling in mouse L cells after 24 hrs by SpringerImages-Topflash reporter assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI