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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
Ki: 2.18E+3nM
Assay Description:
Inhibition of human cytosolic carbonic anhydrase 2 by stopped flow CO2 hydration assay
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
Ki: 4.34E+3nM
Assay Description:
Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assay
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Target
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: 2.75E+3nM
Assay Description:
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...
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Target
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1...
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Target
Protein mono-ADP-ribosyltransferase PARP16
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal His-tagged human ARTD15 (1 to 280 residues) expressed in Escherichia coli Rosetta2 (DE3) after 24 hrs in presence of NAD+
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Target
Protein mono-ADP-ribosyltransferase PARP12
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD12 (469 to 701 residues) expressed in Escherichia coli Rosetta2 (DE3) after 20 hrs in...
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Target
Protein mono-ADP-ribosyltransferase PARP14
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD8 (1535 to 1801 residues) expressed in Escherichia coli Rosetta2 (DE3) after 21 hrs i...
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Target
Protein mono-ADP-ribosyltransferase PARP15
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 h...
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Target
Nicotinamide N-methyltransferase
(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of human NNMT at 30 uM preincubated for 30 mins followed by nicotinamide substrate and SAM addition measured after 60 mins by fluorescence...
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Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: 5.70E+4nM
Assay Description:
Inhibition of N-terminal His-tagged human ARTD1 (1 to 1014 residues) expressed in Escherichia coli Rosetta2 (DE3) using activated DNA as substrate af...
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Target
Protein mono-ADP-ribosyltransferase PARP4
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: 6.50E+4nM
Assay Description:
Inhibition of N-terminal His-tagged human ARTD4 (250 to 565 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 2.5 ...
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Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
Copy SMILES
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Affinity Data
IC50: 7.70E+4nM
Assay Description:
Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD2 (1 to 583 residues) expressed in Escherichia coli Rosetta2 (DE3) using activated DN...
More data for this Ligand-Target Pair
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Target
Protein mono-ADP-ribosyltransferase PARP3
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
Copy SMILES
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of N-terminal His-tagged thioredoxin-fused human ARTD3 (1 to 533 residues) expressed in Escherichia coli Rosetta2 (DE3) using DNA as subst...
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of N-terminal His-tagged Z-basic-fused human ARTD6 (873 to 1161 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as subst...
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Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Oulu
Curated by
ChEMBL
Ligand
BDBM50340090
(4-methoxybenzamide | CHEMBL449635)
Copy SMILES
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of N-terminal His-tagged human ARTD5 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) using TCEP as substrate after 18...
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