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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
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Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
German University
US Patent
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
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Affinity Data
IC50: 3.80E+3nM
Assay Description:
PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
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In Depth
Details
US Patent
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Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
German University
US Patent
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
German University
US Patent
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Ras-related protein Rab-2A
(Canis lupus familiaris)
Nmmlsc
Curated by
PubChem BioAssay
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
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Affinity Data
EC50: 704nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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MCE
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Cell division control protein 42 homolog
(Homo sapiens (Human))
Nmmlsc
Curated by
PubChem BioAssay
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.04E+3nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Cell division control protein 42 homolog
(Homo sapiens (Human))
Nmmlsc
Curated by
PubChem BioAssay
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.04E+3nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Ras-related protein Rab-2A
(Canis lupus familiaris)
Nmmlsc
Curated by
PubChem BioAssay
Ligand
BDBM43220
(4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 704nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MCE
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI