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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 14 hits in this display   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataKi:  24nMAssay Description:Binding affinity to human CA1 assessed as inhibition constant using p-Nitrophenylacetate as substrate by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataKi:  37nMAssay Description:Binding affinity to human CA2 assessed as inhibition constant using p-Nitrophenylacetate as substrate by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataKi:  620nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataKi:  620nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataIC50:  4.33E+3nMAssay Description:Inhibition of human recombinant COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.98E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  2.92E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54659(4-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydro...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay