Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  6nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  9nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  143nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)
Affinity DataKi:  823nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed