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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
36
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Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 9nM
Assay Description:
Inhibition of PDGFRalpha (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-...
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Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 41nM
Assay Description:
Inhibition of PDGFRbeta (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...
More data for this Ligand-Target Pair
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Target
Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 210nM
Assay Description:
Inhibition of RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 240nM
Assay Description:
Inhibition of KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
NT-3 growth factor receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 500nM
Assay Description:
Inhibition of TRKC (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
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Target
Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 610nM
Assay Description:
Inhibition of KIF5B-RET V804M mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs b...
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Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 770nM
Assay Description:
Inhibition of TRKB (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of LCK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of LYN (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 1.60E+3nM
Assay Description:
Inhibition of KIT (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of SRC (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of FGFR2 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
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Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 3.10E+3nM
Assay Description:
Inhibition of FGFR1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
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Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 3.80E+3nM
Assay Description:
Inhibition of JAK2 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
More data for this Ligand-Target Pair
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Target
Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 4.10E+3nM
Assay Description:
Inhibition of FGR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
More data for this Ligand-Target Pair
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of FMS (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Fibroblast growth factor receptor 4
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 4.40E+3nM
Assay Description:
Inhibition of FGFR4 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
More data for this Ligand-Target Pair
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 4.90E+3nM
Assay Description:
Inhibition of FGFR3 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 8.20E+3nM
Assay Description:
Inhibition of BLK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: 8.70E+3nM
Assay Description:
Inhibition of IGF1R (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
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Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: >8.70E+3nM
Assay Description:
Inhibition of MER (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
More data for this Ligand-Target Pair
Target Info
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Target
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.00E+4nM
Assay Description:
Inhibition of BCR/ABL (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc...
More data for this Ligand-Target Pair
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MMDB
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Target
Insulin receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.00E+4nM
Assay Description:
Inhibition of INSR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
More data for this Ligand-Target Pair
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Target
ALK tyrosine kinase receptor/Nucleophosmin
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.10E+4nM
Assay Description:
Inhibition of NPM/ALK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc...
More data for this Ligand-Target Pair
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Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.10E+4nM
Assay Description:
Inhibition of TYRO3 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
More data for this Ligand-Target Pair
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: >1.10E+4nM
Assay Description:
Inhibition of TRKA (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
More data for this Ligand-Target Pair
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Target
Tyrosine-protein kinase receptor Tie-1
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.10E+4nM
Assay Description:
Inhibition of TIE1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
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Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.10E+4nM
Assay Description:
Inhibition of SYK (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
More data for this Ligand-Target Pair
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Target
Proto-oncogene tyrosine-protein kinase ROS
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: >1.10E+4nM
Assay Description:
Inhibition of ROS (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
More data for this Ligand-Target Pair
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Target
Macrophage-stimulating protein receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.10E+4nM
Assay Description:
Inhibition of RON (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: >1.10E+4nM
Assay Description:
Inhibition of MET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
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Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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IC50: >1.10E+4nM
Assay Description:
Inhibition of FLT1 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: >1.10E+4nM
Assay Description:
Inhibition of FLT3 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucife...
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
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Affinity Data
IC50: >1.10E+4nM
Assay Description:
Inhibition of ZAP70 (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucif...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation
Curated by
ChEMBL
Ligand
BDBM50538509
(CHEMBL4636995)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.10E+4nM
Assay Description:
Inhibition of BMX (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-lucifer...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI