Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 5 hits in this display
BDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
IC50: 7.80E+3nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) using acetylthiocholine iodide as substrate incubated for 10 mins by Ellman's colorimetric methodMore data for this Ligand-Target Pair
BDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
IC50: 9.06E+3nMAssay Description:Inhibition of human MAO-B preincubated for 30 mins followed by substrate addition and measured for 10 to 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
BDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
BDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
IC50: 6.30E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
BDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
IC50: >1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair