Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 7 hits in this display
Beta-glucuronidase(Escherichia coli (Enterobacteria))University of North Carolina At Chapel Hill
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Ki: 1.10E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Beta-galactosidase(Streptococcus agalactiae (Firmicutes))University of North Carolina At Chapel Hill
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Ki: 3.00E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Beta-glucuronidase(Homo sapiens (Human))University of North Carolina At Chapel Hill
US Patent
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Beta-glucuronidase(Homo sapiens (Human))University of North Carolina At Chapel Hill
US Patent
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Beta-glucuronidase(Homo sapiens (Human))University of North Carolina At Chapel Hill
US Patent
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
EC50: 28.3nMAssay Description:PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair
Beta-glucuronidase(Homo sapiens (Human))University of North Carolina At Chapel Hill
US Patent
BDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
EC50: 33.2nMAssay Description:PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...More data for this Ligand-Target Pair