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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50188561
(CHEMBL3827963)
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Affinity Data
IC50: 106nM
Assay Description:
Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50188561
(CHEMBL3827963)
Copy SMILES
Copy InChI
Affinity Data
IC50: 111nM
Assay Description:
Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 2
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50188561
(CHEMBL3827963)
Copy SMILES
Copy InChI
Affinity Data
IC50: 259nM
Assay Description:
Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Bath
Curated by
ChEMBL
Ligand
BDBM50188561
(CHEMBL3827963)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI