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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProbable G-protein coupled receptor 139(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263499((s)-n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...)
Affinity DataKi:  11nM ΔG°:  -42.2kJ/molepH: 7.4 T: 4°CAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProbable G-protein coupled receptor 139(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263499((s)-n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...)
Affinity DataKi:  11nMAssay Description:Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetProbable G-protein coupled receptor 139(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM263499((s)-n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...)
Affinity DataKi:  1.10E+4nMAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent