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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
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Target
Probable G-protein coupled receptor 139
(Human)
Takeda Pharmaceutical
US Patent
Ligand
BDBM263499
((s)-n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...)
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Affinity Data
Ki: 11nM ΔG°: -42.2kJ/mole
pH: 7.4 T: 4°C
Assay Description:
This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Probable G-protein coupled receptor 139
(Human)
Takeda Pharmaceutical
US Patent
Ligand
BDBM263499
((s)-n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Probable G-protein coupled receptor 139
(Human)
Takeda Pharmaceutical
US Patent
Ligand
BDBM263499
((s)-n-(1-(2-fluoro-4-(trifluoromethyl)phenyl)ethyl...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10E+4nM
Assay Description:
This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI