Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610454(N-(4-(Methylsulfonyl)pyridin-3-yl)-2-phenylimidazo...)
Affinity DataIC50:  0.400nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610454(N-(4-(Methylsulfonyl)pyridin-3-yl)-2-phenylimidazo...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length GST-tagged human recombinant GSK3-alpha using FL-KRREILSRRP[ps]ERYR-NH2 as substrate incubated for 20 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610454(N-(4-(Methylsulfonyl)pyridin-3-yl)-2-phenylimidazo...)
Affinity DataIC50:  1.5nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM610454(N-(4-(Methylsulfonyl)pyridin-3-yl)-2-phenylimidazo...)
Affinity DataIC50:  120nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent