Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL

LigandBDBM50188307(2-(3-(7-chloroquinolin-4-yl)-2,5-dimethyl-1H-indol...)Copy SMILESCopy InChI

Affinity DataIC50:  8nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL

LigandBDBM50188307(2-(3-(7-chloroquinolin-4-yl)-2,5-dimethyl-1H-indol...)Copy SMILESCopy InChI

Affinity DataIC50:  400nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI