Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataKi:  68nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataKi:  68nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human DP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataIC50:  67nMAssay Description:Concentration required to inhibit PGD-2 induced chemotaxis of Th2 cells expressing CRTH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataIC50:  74nMAssay Description:Concentration required to inhibit PGD-2 induced change in the shape of human eosinophils expressing CRTH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataIC50:  106nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Oxagen

Curated by ChEMBL
LigandPNGBDBM50174351(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Affinity DataIC50:  158nMAssay Description:Concentration required to inhibit PGD-2 (10 nM) stimulated [Ca2+] flux in CHO cells expressing human CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed