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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
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Affinity Data
Ki: 68nM
Assay Description:
Binding affinity towards human CRTH2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 68nM
Assay Description:
Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity towards human DP receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Concentration required to inhibit PGD-2 induced chemotaxis of Th2 cells expressing CRTH2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 74nM
Assay Description:
Concentration required to inhibit PGD-2 induced change in the shape of human eosinophils expressing CRTH2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 106nM
Assay Description:
Inhibition of CRTH2 in human whole blood
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Oxagen
Curated by
ChEMBL
Ligand
BDBM50174351
(CHEMBL196707 | [5-Fluoro-1-(4-methanesulfonyl-benz...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 158nM
Assay Description:
Concentration required to inhibit PGD-2 (10 nM) stimulated [Ca2+] flux in CHO cells expressing human CRTH2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI