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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296849
(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)
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Affinity Data
Ki: 35nM
Assay Description:
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296849
(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
Assay Description:
Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296849
(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 41nM
Assay Description:
Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50296849
(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 56nM
Assay Description:
Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape change
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI