Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO/Ga16 cells co-expressing Galpha16 protein assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50:  3.10E+4nMAssay Description:Displacement of [3H]Dofetilide from human CRTH2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of [3H]PGD2 from human DP1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed