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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
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Affinity Data
IC50: 0.800nM
Assay Description:
Binding affinity to human CRTH2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of CRTH2 receptor-mediated chemotaxis in human basophils
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
Assay Description:
Displacement of [3H]PGD2 from recombinant human CRTH2 receptor expressed in CHO-K1 cells after 30 min by FRET method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Mus musculus (mouse))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
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Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Inhibition of mouse CRTH2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 2A6
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
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Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP2A6
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
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Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
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Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP2B6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C8
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP2C8
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90E+4nM
Assay Description:
Binding affinity to DP1 receptor by FRET assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50401097
(CHEMBL2204469)
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Copy InChI
Affinity Data
IC50: 5.60E+5nM
Assay Description:
Antagonist activity at TXA2 receptor by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI