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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50197203(CHEMBL3910011)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50197203(CHEMBL3910011)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed