Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Soochow University

Curated by ChEMBL

LigandBDBM50458259(CHEMBL4215992)Copy SMILESCopy InChI

Affinity DataIC50:  0.720nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSmoothened homolog(Mus musculus)
Soochow University

Curated by ChEMBL

LigandBDBM50458259(CHEMBL4215992)Copy SMILESCopy InChI

Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse NIH3T3 cells expressing GRE-Luc reporter gene assessed as inhibition of SAG-induced GR...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI