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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by
ChEMBL
Ligand
BDBM50231890
(2-((2-carboxyethyl)carbamoyl)-6-methyl-3-phenethyl...)
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Affinity Data
IC50: 4.90E+5nM
Assay Description:
Binding affinity to GST tagged human CFTR PDZ2 domain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Segment polarity protein dishevelled homolog DVL-3
(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by
ChEMBL
Ligand
BDBM50231890
(2-((2-carboxyethyl)carbamoyl)-6-methyl-3-phenethyl...)
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Copy InChI
Affinity Data
IC50: >5.00E+5nM
Assay Description:
Antagonist activity at human Dvl3 assessed as inhibition of interaction between Dvl3 PDZ domain and Fz7 PDZ domain by alphaScreen assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Segment polarity protein dishevelled homolog DVL-1
(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by
ChEMBL
Ligand
BDBM50231890
(2-((2-carboxyethyl)carbamoyl)-6-methyl-3-phenethyl...)
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Copy InChI
Affinity Data
IC50: >5.00E+5nM
Assay Description:
Antagonist activity at human Dvl1 assessed as inhibition of interaction between Dvl1 PDZ domain and Fz7 PDZ domain by alphaScreen assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by
ChEMBL
Ligand
BDBM50231890
(2-((2-carboxyethyl)carbamoyl)-6-methyl-3-phenethyl...)
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Copy InChI
Affinity Data
IC50: 8.20E+5nM
Assay Description:
Binding affinity to GST tagged human beta 2 adrenergic receptor PDZ1 domain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI