Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCoagulation factor IX(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50125961(CHEMBL3627870)Copy SMILESCopy InChI

Affinity DataKi:  19nMAssay Description:Inhibition of human coagulation factor 9a using fluorescent peptide CH3SO2-D-CHG-Gly-Arg-AFC-AcoH as substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor X(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50125961(CHEMBL3627870)Copy SMILESCopy InChI

Affinity DataKi:  412nMAssay Description:Inhibition of human coagulation factor 10a using fluorescent peptide nAcetyl-KPR-AFC as substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCoagulation factor IX(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM324214(US10189819, Example 51)Copy SMILES

Affinity DataIC50:  19.3nMAssay Description:Formation of a clot to stem bleeding at a site of blood vessel injury involves the coordinated activity of a group of plasma proteins that initiate a...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI