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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613764(N-(2-chloro-4-methylphenyl)-5-(1-cyclohexyl-4-(4-f...)
Affinity DataIC50:  19nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613764(N-(2-chloro-4-methylphenyl)-5-(1-cyclohexyl-4-(4-f...)
Affinity DataIC50:  19nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613764(N-(2-chloro-4-methylphenyl)-5-(1-cyclohexyl-4-(4-f...)
Affinity DataIC50:  71.7nMAssay Description:The MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 uM, 10 mM MgAcetate and [gamma-33P-ATP] (specific activity and concentration as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent