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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute Of Chemical And Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of recombinant GST-tagged p38alpha MAP kinase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Institute Of Chemical And Engineering Sciences

Curated by ChEMBL
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  4.70nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  150nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  150nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  454nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM50491730(CHEMBL2385555 | US10865384, Compound IM-19)
Affinity DataIC50:  454nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent