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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Institute Of Chemical And Engineering Sciences
Curated by
ChEMBL
Ligand
BDBM50491730
(CHEMBL2385555 | US10865384, Compound IM-19)
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Affinity Data
IC50: 4.70nM
Assay Description:
Inhibition of recombinant GST-tagged p38alpha MAP kinase (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Institute Of Chemical And Engineering Sciences
Curated by
ChEMBL
Ligand
BDBM50491730
(CHEMBL2385555 | US10865384, Compound IM-19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70nM
Assay Description:
Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Ligand
BDBM50491730
(CHEMBL2385555 | US10865384, Compound IM-19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Ligand
BDBM50491730
(CHEMBL2385555 | US10865384, Compound IM-19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Ligand
BDBM50491730
(CHEMBL2385555 | US10865384, Compound IM-19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 454nM
Assay Description:
Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Ligand
BDBM50491730
(CHEMBL2385555 | US10865384, Compound IM-19)
Copy SMILES
Copy InChI
Affinity Data
IC50: 454nM
Assay Description:
Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI