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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human tankyrase2 after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human tankyrase1 after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)
Affinity DataIC50:  795nMAssay Description:Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Mus musculus)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)
Affinity DataIC50:  870nMAssay Description:Inhibition of the DNA repair Poly (ADP-ribose) polymerase 1, in permeabilised L1210 murine leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50068758(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant IMPDH2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed