Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCoagulation factor IX(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent

LigandBDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
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TargetCoagulation factor IX(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent

LigandBDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)Copy SMILESCopy InChI

Affinity DataIC50:  550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails US PatentPDB3D Structure (crystal)
Copy BDB DOI