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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 13 hits in this display   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  64nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DDR2 (467 to end residues) expressed in baculovirus infected Sf21 insect cells using Axltide a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged c-RAF Y340D/Y341D double mutant (306 to 648 residues) expressed in baculovirus infected Sf21 in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  145nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FGFR1 (456 to 765 residues) expressed in baculovirus infected Sf21 insect cells using IGF-IRtid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  208nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged Tie2 (771 to end residues) expressed in baculovirus infected Sf21 insect cells using Poly (Glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  258nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MELK (1 to 340 residues) expressed in baculovirus infected Sf21 insect cells using KKLNRTLSFAEP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50:  527nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells using MBP as sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chung-Ang University

Curated by ChEMBL
LigandPNGBDBM50518408(CHEMBL4483816)
Affinity DataIC50: >5.00E+4nMAssay Description:Displacement of Tracer Red from human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed