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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
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Affinity Data
IC50: 110nM
Assay Description:
Inhibition of cKIT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of c-Kit by HTRF method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 339nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 340nM
Assay Description:
The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 891nM
Assay Description:
Inhibition of Tie2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Dalian University
Curated by
ChEMBL
Ligand
BDBM8837
(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 900nM
Assay Description:
The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI