Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

LigandBDBM50519733(CHEMBL4446778)Copy SMILESCopy InChI

Affinity DataIC50:  37nMAssay Description:Inhibition of wild type recombinant GST-tagged FLT3 (Y567 to S993 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

LigandBDBM50519733(CHEMBL4446778)Copy SMILESCopy InChI

Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant N-terminal 6x-His-tagged c-KIT (547 to 935 residues)/(694 to 753 residues deletion) (unknown origin) expressed in baculovir...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI