Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
University of Kwazulu-Nata
Ligand
BDBM153386
(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+3nM
pH: 8.5 T: 2°C
Assay Description:
The synthesized compounds were assayed for the inhibitory activities against MMP-2 in 96-well microtiter plates using succinylated gelatin as the sub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
University of Kwazulu-Nata
Ligand
BDBM153386
(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+3nM
Assay Description:
Inhibition of MMP-2 (unknown origin) using succinylated gelatin as substrate incubated for 80 mins by microplate reader
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Macrophage metalloelastase
(Homo sapiens (Human))
University of Kwazulu-Nata
Ligand
BDBM153386
(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90E+4nM
pH: 8.0 T: 2°C
Assay Description:
The synthesized compounds were assayed for the inhibitory activities against MMP-12 in 96-well microtiter plates using thiopeptolide as the substrate...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI