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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Kwazulu-Nata

LigandPNGBDBM153386(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Affinity DataIC50:  1.80E+3nMpH: 8.5 T: 2°CAssay Description:The synthesized compounds were assayed for the inhibitory activities against MMP-2 in 96-well microtiter plates using succinylated gelatin as the sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University of Kwazulu-Nata

LigandPNGBDBM153386(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MMP-2 (unknown origin) using succinylated gelatin as substrate incubated for 80 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University of Kwazulu-Nata

LigandPNGBDBM153386(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Affinity DataIC50:  2.90E+4nMpH: 8.0 T: 2°CAssay Description:The synthesized compounds were assayed for the inhibitory activities against MMP-12 in 96-well microtiter plates using thiopeptolide as the substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed