Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50238415(CHEMBL1446017)Copy SMILESCopy InChI

Affinity DataIC50:  398nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50238415(CHEMBL1446017)Copy SMILESCopy InChI

Affinity DataIC50:  1.26E+3nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI