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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: 91nM
Assay Description:
Inhibition of recombinant human FMS (538 to end residues) using KKKSPGEYVNIEFG as substrate measured after 40 mins in presence of [gamma33P]ATP by ra...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: 276nM
Assay Description:
Inhibition of human TYK2 (875 to end residues) using GGMEDIYFEFMGGKKK as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase ULK2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: 1.74E+3nM
Assay Description:
Inhibition of recombinant human ULK2 (1to 306 residues) using casein as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by radiometric...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: 2.74E+3nM
Assay Description:
Inhibition of human TTBK1 (1 to 479 residues) using Casein as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: 5.06E+3nM
Assay Description:
Inhibition of NanoLuc-fused CSF1R (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of NanoLuc-fused TYK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human ERBB2 (676 to 1255 residues) using poly(Glu:Tyr) as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585195
(CHEMBL5089987)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI