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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
hits in this display
Target
BMP-2-inducible protein kinase
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 38nM
Assay Description:
Inhibition of recombinant human BIKe using peptide as substrate incubated for 120 mins in presence of [gamma-33ATP] by scintillation counting based r...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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antibodypedia
GoogleScholar
Ligand Info
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Article
PubMed
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 66nM
Assay Description:
Inhibition of human TTBK1 (1 to 479 residues) using Casein as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting...
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Target Info
PDB
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KEGG
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 67nM
Assay Description:
Inhibition of human TYK2 (875 to end residues) using GGMEDIYFEFMGGKKK as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric...
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Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 80nM
Assay Description:
Inhibition of human AAK1 using peptide as substrate incubated for 120 mins in presence of [gamma-33ATP] by scintillation counting based radiometry as...
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KEGG
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Target
Serine/threonine-protein kinase 16
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 88nM
Assay Description:
Inhibition of human STK16 in presence of [gamma-33P-ATP] by radiometric scintillation assay
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 158nM
Assay Description:
Inhibition of human TrkA (440 to end residues) using KKKSPGEYVNIEFG as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation...
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Target Info
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Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 171nM
Assay Description:
Inhibition of recombinant human ARK5 (2 to end residues) using KKKVSRSGLYRSPSMPENLNRPR as substrate incubated for 40 mins in presence of [gamma-33ATP...
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 192nM
Assay Description:
Inhibition of recombinant human FMS (538 to end residues) using KKKSPGEYVNIEFG as substrate measured after 40 mins in presence of [gamma33P]ATP by ra...
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Target
BMP-2-inducible protein kinase
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 1.02E+3nM
Assay Description:
Inhibition of NanoLuc-fused BMP2K (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
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Article
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Target
Serine/threonine-protein kinase ULK3
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 1.37E+3nM
Assay Description:
Inhibition of full length recombinant human ULK3 using casein as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by radiometric scinti...
More data for this Ligand-Target Pair
Target Info
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KEGG
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Article
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Target
Casein kinase II subunit alpha'
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 2.30E+3nM
Assay Description:
Inhibition of full length recombinant human CSNK2A2 using RRRDDDSDDD a substrate incubated for 40 mins in presence of [gamma-33P-ATP] by radiometric ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: 7.01E+3nM
Assay Description:
Inhibition of NanoLuc-fused NUAK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
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PubMed
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
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Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of full length recombinant human PIP5K1A using phosphatidylinositol 4-phosphate/phosphatidylserine as substrate incubated for 30 mins in p...
More data for this Ligand-Target Pair
Target Info
NCI pathway
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KEGG
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Target
Serine/threonine-protein kinase PRP4 homolog
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human PRP4 (663 to end residues) using casein as substrate incubated for 120 mins in presence of [gamma-33P-ATP] by radiome...
More data for this Ligand-Target Pair
Target Info
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PC sid
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Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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antibodypedia
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PC sid
In Depth
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Article
PubMed
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Target
Casein kinase II subunit alpha
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585189
(CHEMBL5083125)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of full length recombinant human CSNK2A1 using RRRDDDSDDD as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by radiometric...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI