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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Serine/threonine-protein kinase 17B
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 161nM
Assay Description:
Inhibition of recombinant human DRAK2 using KKRPQRRYSNVF as substrate after 120 mins in presence of [gamma-33ATP] by scintillation counting based rad...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 325nM
Assay Description:
Inhibition of recombinant human DRAK1 using KKLNRTLSFAEPG as substrate after 40 mins in presence of [gamma-33ATP] by scintillation counting based rad...
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Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 390nM
Assay Description:
Inhibition of human AAK1 using peptide as substrate incubated for 120 mins in presence of [gamma-33ATP] by scintillation counting based radiometry as...
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Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase SIK2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 481nM
Assay Description:
Inhibition of recombinant human SIK2 (1 to 276 residues) using KKKVSRSGLYRSPSMPENLNRPR as substrate measured after 40 mins in presence of [gamma33P]A...
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Target Info
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Article
PubMed
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 720nM
Assay Description:
Inhibition of human TYK2 (875 to end residues) using GGMEDIYFEFMGGKKK as substrate measured after 40 mins in presence of [gamma33P]ATP by radiometric...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC sid
In Depth
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Article
PubMed
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Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 769nM
Assay Description:
Inhibition of full length recombinant human MKNK2 using myelin basic protein as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by rad...
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Target Info
PDB
MMDB
KEGG
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GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: 2.31E+3nM
Assay Description:
Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
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Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC sid
In Depth
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Article
PubMed
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Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase TBK1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50585186
(CHEMBL5075360)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI