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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Neprilysin
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50286715
((S)-3-biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-pro...)
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Affinity Data
Ki: 1.10nM
Assay Description:
Inhibition of human recombinant NEP by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Angiotensin-converting enzyme
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50286715
((S)-3-biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-pro...)
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Affinity Data
Ki: 30nM
Assay Description:
Inhibition of human recombinant ACE by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiotensin-converting enzyme 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50286715
((S)-3-biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-pro...)
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Copy InChI
Affinity Data
Ki: 86nM
Assay Description:
Inhibition of human recombinant ACE2 by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxypeptidase A1
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50286715
((S)-3-biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-pro...)
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Affinity Data
Ki: 1.20E+3nM
Assay Description:
Inhibition of human recombinant carboxy peptidase A1 by fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiotensin-converting enzyme 2
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50286715
((S)-3-biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-pro...)
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Copy InChI
Affinity Data
IC50: 80nM
Assay Description:
Inhibition of angiotensin converting enzyme (ACE)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Neprilysin
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50286715
((S)-3-biphenyl-4-yl-2-((S)-2-mercapto-3-phenyl-pro...)
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Copy InChI
Affinity Data
IC50: 654nM
Assay Description:
Inhibition of neutral endopeptidase (NEP) 24.11
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI