Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

LigandBDBM50571865(CHEMBL4863142)Copy SMILESCopy InChI

Affinity DataIC50:  99nMAssay Description:Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

LigandBDBM50571865(CHEMBL4863142)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of APN (unknown origin) using Ala-AMC as substrateMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Sanofi

Curated by ChEMBL

LigandBDBM50571865(CHEMBL4863142)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ERAP2 (unknown origin) using Arg-AMC as substrateMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI